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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1282192Generated: October 31, 2026

1-(2-Pyridyl)piperazine → N-(1-(4-(1-(4-(pyridin-2-yl)piperazin-1-yl)ethyl)phenyl)-1-methylethyl)acetamide

https://huagongshe.com/reaction/1282192

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Pyridyl)piperazineHCID 94459—
ReactantN-(1-(4-(1-chloroethyl)phenyl)-1-methylethyl)acetamideHCID 18423053—
ProductN-(1-(4-(1-(4-(pyridin-2-yl)piperazin-1-yl)ethyl)phenyl)-1-methylethyl)acetamideHCID 11632018—

Reaction Steps

By similar reaction and treatment to that in Example 1(5) using 1-(2-pyridyl)piperazine instead of phenylpiperazine and N-(1-(4-(1-chloroethyl)phenyl)-1-methylethyl)acetamide instead of N-(4-chloromethylphenylmethyl) acetamide, the title compound was obtained as white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06455528B1
Source datasetuspto-grants-2002_09
ORD IDord-02b5fdcf43934d82a7a0e466969c0b6b
Source noteuspto-grants-2002_09