Sulfuric Acid → 2-Methylchromone

HRID 1282249Notes

Reaction equation

HRID 1282249 reaction equation
S(=O)(=O)(O)O.[C:6]([CH2:9][C:10]([C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)=[O:11])(=[O:8])[CH3:7]>O>[CH3:7][C:6]1[O:8][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=2[C:10](=[O:11])[CH:9]=1

Participants

4

Reactant 2

HCID 1118Sulfuric AcidHCID 7166Benzoylacetone

Product 1

HCID 2526902-MethylchromoneYield 74%

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Concentrated sulphuric acid (30 g) is added to acetyl acetophenone (15 g) obtained as above described. After cooling at room temperature, water is added until precipitation of a white powder, which is isolated by filtration under vacuum and washed with cold water. 2-methyl-4H-1-benzopyran-4-one (10 g) is obtained (m.p.=71° C.; yield=74%).

Workup

  1. customobtained
  2. customwhich is isolated by filtration under vacuum
  3. washwashed with cold water

Sources & evidence

ORD record
ord-d52e18c19c6645ee8409ed28a72c7be2
Source dataset
uspto-grants-2002_09
Patent number
US06455578B1

Reaction notes

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