Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Acetic Acid | HCID 176 | — |
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 5-Methylisatoic anhydride | HCID 294478 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 10400153 | HCID 10400153 | — |
Reaction Steps
To a suspension of 5-methyl-isatoic anhydride (9.2 g, 0.052 mol) in a mixture of glacial acetic acid (60 mL) and TFA (30 mL), bromine (9.9 g, 0.062 mol) was added under stirring at 5° C. Reaction mixture warmed to room temperature and stirred˜5 hours. Poured in cold water and yellow ppt filtered and washed with water and dried. Yield: 12.09 g, 90%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06455698B1 |
|---|
| Source dataset | uspto-grants-2002_09 |
|---|
| ORD ID | ord-2dffaa312b5146b099e42e11fd4c9b22 |
|---|
| Source note | uspto-grants-2002_09 |
|---|
