反应详情

A solution of 2-butylamino-4-methyloxazole (10.0 g, 0.065 mol) and hexyl isocyanate (8.25 g, 0.065 mol) in dry benzene was heated under reflux for 3 hours. The solution was evaporated and the residual oil dissolved in ether, washed with dilute HCl, dried and re-evaporated. The residue was dissolved in petroleum spirit (40°-60° C.) carbon treated and re-evaporated under vacuum to give the pure product as a pale oil.

1. temperatureunder reflux for 3 hours
2. customThe solution was evaporated
3. dissolutionthe residual oil dissolved in ether
4. washwashed with dilute HCl
5. customdried
6. customre-evaporated
7. dissolutionThe residue was dissolved in petroleum spirit (40°-60° C.) carbon
8. additiontreated
9. customre-evaporated under vacuum