反应详情

A solution of 2-butylamino-4-methyloxazole (12.0 g, 0.078 mol) and allyl isocyanate (6.46 g, 0.078 mol) in dry benzene was heated under reflux for 4 hours, and worked up as described in Example 3. The product was further purified by chromatography on a silica-gel column, eluting with a 1:1 mixture of benzene and ethyl acetate.

1. temperatureunder reflux for 4 hours
2. customThe product was further purified by chromatography on a silica-gel column
3. washeluting with a 1:1 mixture of benzene and ethyl acetate