1-Iodohexane → HCID 86584055, compound

HRID 1282389Notes

Reaction equation

[Br:1][C:2]1[C:22]([Br:23])=[CH:21][C:20]([Br:24])=[CH:19][C:3]=1[C:4]([C:6]1[N:10]([CH3:11])[C:9]([CH2:12][C:13]([O:15]CC)=[O:14])=[CH:8][C:7]=1[CH3:18])=[O:5].C(I)CCCCC>>[CH2:12]([C:9]1[N:10]([CH3:11])[C:6]([C:4](=[O:5])[C:3]2[CH:19]=[C:20]([Br:24])[CH:21]=[C:22]([Br:23])[C:2]=2[Br:1])=[C:7]([CH3:18])[CH:8]=1)[CH3:13].[CH2:9]([CH2:12][C:13]([O-:15])=[O:14])[CH2:8][CH2:7][CH2:6][CH2:4][CH3:3]

Participants

Reactant 2

HCID 125271-Iodohexane

HCID 18424339HCID 18424339, compound

Product 1

HCID 86584055HCID 86584055, compound

Procedure

The alkylation procedure of Example 77A is performed upon ethyl 5-(2′,3′,5′-tribromobenzoyl)-1,4-dimethylpyrrole-2-acetate (from Example 91), using an equivalent quantity of n-hexyl iodide instead of methyl iodide used in Example 77A to yield ethyl 5-(2′,3′,5′-tribromobenzoyl)-1,4-dimethylpyrrole-2-(α-n-hexyl)-acetate.

Sources & evidence

ORD record: ord-4884c0e4b9f7408fa05e74e9c27a7740
Source dataset: uspto-grants-2002_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06455703B2

Reaction notes

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