HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2S)-6-(((benzyloxy)carbonyl)amino)-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)hexanoic acid → (2S)-6-amino-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2S)-6-(((benzyloxy)carbonyl)amino)-2-(((9H-fluoren-9-ylmethoxy)carbonyl)amino)hexanoic acid | HCID 3013736 | — |
| Solvent | Trifluoroacetic acid methylene chloride | HCID 21863450 | — |
| Product | (2S)-6-amino-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acid | HCID 7010557 | — |
Reaction Steps
Nα-(9-fluorenylmethoxycarbonyl)-Nε-benzyloxycarbonyl-L-lysine (502 mg, 1.00 mmol) was dissolved in TFA/CH2Cl2 (3 mL/3 mL) and stirred at room temperature for 1 h. The volatiles were removed in vacuo to afford the title compound quantitatively as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06455587B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-62eac48ee4c14558938b608cb3c72138 |
| Source note | uspto-grants-2002_09 |