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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1282486Generated: October 25, 2026

4-Fluorobenzenesulfonyl chloride → Nepsilon-(4-fluorobenzenesulfonyl)-Nalpha-(9-fluorenylmethoxycarbonyl)-L-lysine

https://huagongshe.com/reaction/1282486

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Fluorobenzenesulfonyl chlorideHCID 9588—
Reactant(2S)-6-amino-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acidHCID 7010557—
ProductNepsilon-(4-fluorobenzenesulfonyl)-Nalpha-(9-fluorenylmethoxycarbonyl)-L-lysineHCID 8660431451%

Reaction Steps

Nα-(9-fluorenylmethoxycarbonyl)-L-lysine was reacted with 4-fluorobenzenesulfonyl chloride under the conditions used in example 2 giving 51% of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06455587B1
Source datasetuspto-grants-2002_09
ORD IDord-400438a5b525486cbcc2c5cce80a780b
Source noteuspto-grants-2002_09