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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1282488Generated: October 26, 2026

4-Toluenesulfonyl chloride → (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-(p-tolylsulfonylamino)hexanoic acid

https://huagongshe.com/reaction/1282488

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Toluenesulfonyl chlorideHCID 7397—
Reactant(2S)-6-amino-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)hexanoic acidHCID 7010557—
Product(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-6-(p-tolylsulfonylamino)hexanoic acidHCID 301373771%

Reaction Steps

Nα-(9-fluorenylmethoxycarbonyl)-L-lysine was reacted with 4-methylbenzenesulfonyl chloride under the conditions used in example 2 giving 71% of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06455587B1
Source datasetuspto-grants-2002_09
ORD IDord-b12d6befcdad4cfc80d9628d221a98a3
Source noteuspto-grants-2002_09