Phenoxyacetyl chloride → HCID 86604357, compound

HRID 1282527Notes

Reaction equation

HRID 1282527 reaction equation
[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])[CH:2]([CH3:4])[CH3:3].[O:27]([CH2:34][C:35](Cl)=[O:36])[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:35](=[O:36])[CH2:34][O:27][C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1)[CH:2]([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 69703Phenoxyacetyl chlorideHCID 69107391HCID 69107391, compound

Product 1

HCID 86604357HCID 86604357, compoundYield 88%

Procedure

Nα-isobutyl-Nα-(4-nitrobenzenesulfonyl)-L-lysine was reacted with phenoxyacetyl chloride under the conditions described in example 2 to yield 88% of the desired product.

Sources & evidence

ORD record
ord-a09a6ba17c0d432085efd17ff2b62d56
Source dataset
uspto-grants-2002_09
Patent number
US06455587B1

Reaction notes

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