3',4'-Dimethoxycinnamic acid → HCID 86604360, compound

HRID 1282530Notes

Reaction equation

HRID 1282530 reaction equation
[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])[CH:2]([CH3:4])[CH3:3].[CH3:27][O:28][C:29]1[CH:30]=[C:31]([CH:37]=[CH:38][C:39]=1[O:40][CH3:41])[CH:32]=[CH:33][C:34](O)=[O:35]>>[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:34](=[O:35])[CH:33]=[CH:32][C:31]1[CH:37]=[CH:38][C:39]([O:40][CH3:41])=[C:29]([O:28][CH3:27])[CH:30]=1)[CH:2]([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 168483',4'-Dimethoxycinnamic acidHCID 69107391HCID 69107391, compound

Product 1

HCID 86604360HCID 86604360, compoundYield 73%

Procedure

Nα-isobutyl-Nα-(4-nitrobenzenesulfonyl)-L-lysine was reacted with 3,4-dimethoxycinnamic acid under the conditions described in example 86 to yield 73% of the desired product.

Sources & evidence

ORD record
ord-5f5b99dba53d4342a5dbb24db8f5ae39
Source dataset
uspto-grants-2002_09
Patent number
US06455587B1

Reaction notes

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