trans-3-(3-Pyridyl)acrylic acid → HCID 86604361, compound

HRID 1282531Notes

Reaction equation

HRID 1282531 reaction equation
[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH2:11])[CH:2]([CH3:4])[CH3:3].[N:27]1[CH:32]=[CH:31][CH:30]=[C:29](/[CH:33]=[CH:34]/[C:35](O)=[O:36])[CH:28]=1>>[CH2:1]([N:5]([S:15]([C:18]1[CH:23]=[CH:22][C:21]([N+:24]([O-:26])=[O:25])=[CH:20][CH:19]=1)(=[O:17])=[O:16])[C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][CH2:9][CH2:10][NH:11][C:35](=[O:36])/[CH:34]=[CH:33]/[C:29]1[CH:28]=[N:27][CH:32]=[CH:31][CH:30]=1)[CH:2]([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 776396trans-3-(3-Pyridyl)acrylic acidHCID 69107391HCID 69107391, compound

Product 1

HCID 86604361HCID 86604361, compoundYield 60%

Procedure

Nα-isobutyl-Nα-(4-nitrobenzenesulfonyl)-L-lysine was reacted with trans-3-(3-pyridyl)acrylic acid under the conditions described in example 86 to yield 60% of the desired product.

Sources & evidence

ORD record
ord-30ce30c94af440afa5fea7825c1e94ff
Source dataset
uspto-grants-2002_09
Patent number
US06455587B1

Reaction notes

Loading…