HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Nitrobenzoic acid → 4-[[(2-nitrophenyl)carbonyl]amino]-N-[[1-(phenylmethyl)cyclopentyl]carbonyl]-L-phenylalanine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Nitrobenzoic acid | HCID 11087 | — |
| Reactant | 4-amino-N-[[1-(phenylmethyl)cyclopentyl]carbonyl]-L-phenylalanine methyl ester | HCID 53841867 | — |
| Product | 4-[[(2-nitrophenyl)carbonyl]amino]-N-[[1-(phenylmethyl)cyclopentyl]carbonyl]-L-phenylalanine | HCID 10152525 | 62.4% |
Reaction Steps
4-Amino-N-[[1-(phenylmethyl)cyclopentyl]carbonyl]-L-phenylalanine methyl ester (31.7 mg, 0.083 mmol) and 2-nitrobenzoic acid (38 mg, 0.10 mmol) were reacted as described in example 34 to give 26.7 mg of 4-[[(2-nitrophenyl)carbonyl]amino]-N-[[1-(phenylmethyl)cyclopentyl]carbonyl]-L-phenylalanine, HR-FAB-MS: obs. mass 516.2113. Calcd. mass 516.2134 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06455550B1 |
| Source dataset | uspto-grants-2002_09 |
| ORD ID | ord-77c2d8106a864108a4c14d2b91dba896 |
| Source note | uspto-grants-2002_09 |