4-Chloroaniline → HCID 70578699, compound

HRID 128263Notes

Reaction equation

HRID 128263 reaction equation
[OH:1][C:2]1[C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[S:5](=[O:16])(=[O:15])[N:4]([CH3:17])[C:3]=1[C:18]([O:20]CC1C=CC=CC=1)=O.[Cl:28][C:29]1[CH:35]=[CH:34][C:32]([NH2:33])=[CH:31][CH:30]=1>>[Cl:28][C:29]1[CH:35]=[CH:34][C:32]([NH:33][C:18]([C:3]2[N:4]([CH3:17])[S:5](=[O:16])(=[O:15])[C:6]3[C:10]4[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=4[S:8][C:7]=3[C:2]=2[OH:1])=[O:20])=[CH:31][CH:30]=1

Participants

3

Reactant 2

HCID 78124-ChloroanilineHCID 70577953HCID 70577953, compound

Product 1

HCID 70578699HCID 70578699, compoundYield 52%

Procedure

Prepared analogous to Example 1 from benzyl 4-hydroxy-2-methyl-2H-[1]-benzothieno[2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 4-chloro-aniline with a yield of 52% of theory.

Sources & evidence

ORD record
ord-fa62ca5a11f84691b5e1420877e02c73
Source dataset
uspto-grants-1981_03
Patent number
US04259336

Reaction notes

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