4-tert-Butyl-1,3-thiazol-2-amine → HCID 86737636, compound

HRID 128269Notes

Reaction equation

HRID 128269 reaction equation
[OH:1][C:2]1[C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[S:5](=[O:16])(=[O:15])[N:4]([CH3:17])[C:3]=1[C:18](OC)=[O:19].[CH3:22][C:23]([C:26]1[N:27]=[C:28]([NH2:31])[S:29][CH:30]=1)([CH3:25])[CH3:24]>>[CH3:22][C:23]([C:26]1[N:27]=[C:28]([NH:31][C:18]([C:3]2[N:4]([CH3:17])[S:5](=[O:16])(=[O:15])[C:6]3[C:10]4[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=4[S:8][C:7]=3[C:2]=2[OH:1])=[O:19])[S:29][CH:30]=1)([CH3:25])[CH3:24]

Participants

3

Reactant 2

HCID 27342024-tert-Butyl-1,3-thiazol-2-amineHCID 547072593-carbomethoxy-4-hydroxy-2-methyl-2H-[1]benzothieno[2,3-e]-1,2-thiazine 1,1-dioxide

Product 1

HCID 86737636HCID 86737636, compoundYield 33%

Procedure

Prepared analogous to Example 1 from methyl 4-hydroxy-2-methyl-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 4-(1,1-dimethyl-ethyl)-2-thiazolamine with a yield of 33% of theory.

Sources & evidence

ORD record
ord-8cc2bbbff4d34e0091d342b376579153
Source dataset
uspto-grants-1981_03
Patent number
US04259336

Reaction notes

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