Pyridine-3-sulfonyl chloride → HCID 178478583, compound

HRID 1282705Notes

Reaction equation

HRID 1282705 reaction equation
[ClH:1].[NH:2]1[CH:6]=[C:5]([CH2:7][N:8]2[C:14]3[CH:15]=[CH:16][C:17]([C:19]#[N:20])=[CH:18][C:13]=3[CH2:12][N:11]([S:21]([CH3:24])(=[O:23])=[O:22])[C@H:10]([CH2:25][C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[CH2:9]2)[N:4]=[CH:3]1.[N:32]1[CH:37]=C[CH:35]=[C:34](S([Cl:41])(=O)=O)[CH:33]=1>>[ClH:41].[ClH:1].[ClH:41].[C:19]([C:17]1[CH:16]=[CH:15][C:14]2[N:8]([CH2:7][C:5]3[N:4]=[CH:3][NH:2][CH:6]=3)[CH2:9][C@@H:10]([CH2:25][C:26]3[CH:27]=[CH:28][CH:29]=[CH:30][CH:31]=3)[N:11]([S:21]([C:24]3[CH:37]=[N:32][CH:33]=[CH:34][CH:35]=3)(=[O:22])=[O:23])[CH2:12][C:13]=2[CH:18]=1)#[N:20]

Participants

3

Reactant 2

HCID 3164136Pyridine-3-sulfonyl chlorideHCID 178504922HCID 178504922, compound

Product 1

HCID 178478583HCID 178478583, compoundYield 15%

Procedure

Example 387 was prepared as a yellow solid in 15% yield from Compound C of Example 248 and 3-pyridinesulfonyl chloride as described for Example 284.

Sources & evidence

ORD record
ord-7e53bca071f6441899f81b6d14d7dec1
Source dataset
uspto-grants-2002_09
Patent number
US06455523B1

Reaction notes

Loading…