HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydroxylamine → Piroctone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydroxylamine | HCID 787 | — |
| Reactant | 2-Aminopyridine | HCID 10439 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Reactant | 4-Methyl-6-(2,4,4-trimethylpentyl)-2H-pyran-2-one | HCID 18970429 | — |
| Product | Piroctone | HCID 50259 | 66.5% |
Reaction Steps
10 g of 4-methyl-6-(2,4,4-trimethylpentyl)-2-pyrone, 5 g of hydroxylamine hydrochloride and 20 g of 2-aminopyridine were heated for 26 hours to 70°C, whereupon after 17 hours a further 2 g of hydroxylamine were added. Working up was effected as usual and there were obtained 7.1 g (67 %) of 1-hydroxy-4-methyl-6-(2,4,4-trimethylpentyl)-2-pyridone melting at 108° C (Calc.: 5.9 % N, found 5.9 % N).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03972888 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-95dca5aeab3d4714980c7ae8157d70d3 |
| Source note | uspto-grants-1976_08 |