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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 128273Generated: October 26, 2026

3,4,5,6-Tetrahydro-2H-cyclopenta(d)(1,3)thiazol-2-imine → N-(5,6-Dihydro-4H-cyclopentathiazole-2-yl)-4-hydroxy-2-methyl-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxide

https://huagongshe.com/reaction/128273

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4,5,6-Tetrahydro-2H-cyclopenta(d)(1,3)thiazol-2-imineHCID 332255—
Reactant3-carbomethoxy-4-hydroxy-2-methyl-2H-[1]benzothieno[2,3-e]-1,2-thiazine 1,1-dioxideHCID 54707259—
ProductN-(5,6-Dihydro-4H-cyclopentathiazole-2-yl)-4-hydroxy-2-methyl-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxideHCID 8673763957%

Reaction Steps

Prepared analogous to Example 1 from methyl 4-hydroxy-2-methyl-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 5,6-dihydro-4H-cyclopentathiazole-2-amine with a yield of 57% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04259336
Source datasetuspto-grants-1981_03
ORD IDord-0f2eb9fbd17e44598901f780fe921616
Source noteuspto-grants-1981_03