Ethanol → HCID 70601995, compound

HRID 1282739Notes

Reaction equation

HRID 1282739 reaction equation
[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[C:8]2[C:12](=[C:13]([CH3:15])[CH:14]=1)[NH:11][C:10](=S)[CH:9]2C)=[O:5])[CH3:2].C([OH:20])C>[Ni]>[CH2:1]([O:3][C:4]([C:6]1[CH:7]=[C:8]2[C:12](=[C:13]([CH3:15])[CH:14]=1)[NH:11][C:10](=[O:20])[CH2:9]2)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 702EthanolHCID 86733773HCID 86733773, compound

Product 1

HCID 70601995HCID 70601995, compoundYield 67%

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

An 0.80 g (3.01 mmol) portion of the 5-ethoxycarbonyl-7-methyl-3-methylthio-2-oxindole in 130 ml of absolute ethanol was treated with Raney Nickel by the above described procedure to give 0.44 g (2.01 mmol, 67% yield) of 5-ethoxycarbonyl-7-methyl-2-oxindole, m.p. 238°241°;

Sources & evidence

ORD record
ord-d0c82f4df87c4f88a388c7ec22851c93
Source dataset
uspto-grants-1976_08
Patent number
US03972894

Reaction notes

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