2-Aminopyrimidine → HCID 131712142, compound

HRID 128277Notes

Reaction equation

HRID 128277 reaction equation
[OH:1][C:2]1[C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[S:5](=[O:16])(=[O:15])[N:4]([CH3:17])[C:3]=1[C:18](OC)=[O:19].[NH2:22][C:23]1[N:28]=[CH:27][CH:26]=[CH:25][N:24]=1>>[OH:1][C:2]1[C:7]2[S:8][C:9]3[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=3[C:6]=2[S:5](=[O:16])(=[O:15])[N:4]([CH3:17])[C:3]=1[C:18]([NH:22][C:23]1[N:28]=[CH:27][CH:26]=[CH:25][N:24]=1)=[O:19]

Participants

3

Reactant 2

HCID 79782-AminopyrimidineHCID 547072593-carbomethoxy-4-hydroxy-2-methyl-2H-[1]benzothieno[2,3-e]-1,2-thiazine 1,1-dioxide

Product 1

HCID 131712142HCID 131712142, compoundYield 39%

Procedure

Prepared analogous to Example 1 from methyl 4-hydroxy-2-methyl-2H[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and 2-amino-pyrimidine with a yield of 39% of theory.

Sources & evidence

ORD record
ord-632c7007004e4a2c90ee1b0a5d86243b
Source dataset
uspto-grants-1981_03
Patent number
US04259336

Reaction notes

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