Thiophenol → HCID 21520083, compound

HRID 1282772Notes

Reaction equation

HRID 1282772 reaction equation
[CH2:1]([S:8][C:9]1[CH:10]=[C:11]([CH:15]=[C:16]([S:19](=[O:22])(=[O:21])[NH2:20])[C:17]=1Cl)[C:12]([O-:14])=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[C:23]1([SH:29])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1.[C:30]1([S-])C=CC=C[CH:31]=1.[Na+]>C(O)C>[CH2:1]([S:8][C:9]1[CH:10]=[C:11]([CH:15]=[C:16]([S:19](=[O:22])(=[O:21])[NH2:20])[C:17]=1[S:29][C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1)[C:12]([O:14][CH2:30][CH3:31])=[O:13])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

5

Reactant 3

HCID 7969ThiophenolHCID 4110039Sodium benzenethiolateHCID 21520119HCID 21520119, compound

Product 1

HCID 21520083HCID 21520083, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

A mixture of ethyk 3-benzylthio-4-chloro-5-sulfamylbenzoate (0.77 g), thiophenol (0.36 ml), and dry ethanol (15 ml) containing 3millimoles of sodium thiophenolate is refulxed for 20 hours. After cooling the precipitate is collected by filtration to yield ethyl 3-benzylthio-4-phenylthio-5-sulfamylbenzoate with a melting point of 151° - 152°C.

Workup

  1. temperatureAfter cooling the precipitate
  2. filtrationis collected by filtration

Sources & evidence

ORD record
ord-43d2d511c85a4fc4b5cb5fae626db0b1
Source dataset
uspto-grants-1976_08
Patent number
US03972886

Reaction notes

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