HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus pentachloride → 2-Chlorocarbonyl-6-methyl-benzo[b] thiophene-3-sulfonic acid chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus pentachloride | HCID 24819 | — |
| Reactant | Monosodium 2-carboxy-6-methyl-benzo[b] thiophene-3-sulfonate | HCID 86737645 | — |
| Reactant | HCID 178527001 | HCID 178527001 | — |
| Product | 2-Chlorocarbonyl-6-methyl-benzo[b] thiophene-3-sulfonic acid chloride | HCID 53874516 | 82% |
Reaction Steps
Prepared analogous to Example 1(b) from monosodium 2-carboxy-6-methyl-benzo[b] thiophene-3-sulfonate and phosphorus-(V)-chloride in the presence of phosphorus oxide trichloride with a yield of 82% of theory. The product, which crystallized upon cooling, was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04259336 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-9f28a53b1eba47459e14931769153081 |
| Source note | uspto-grants-1981_03 |