N-bromobutanimide → HCID 21520278, compound

Participants

Reaction Conditions

Reaction Steps

28.0 g of recrystallized N-bromosuccinimide were added to a solution of 32.5 g of 7-ethyl-2-(2-methyl-1,3-dioxolan-2-yl)benzofuran in 480 ml of carbon tetrachloride. The resulting suspension was stirred and heated under reflux for 12 hours. The mixture was cooled overnight at 0°C, precipitated succinimide was filtered off and the filtrate was evaporated at 30°C under reduced pressure. There was thus obtained crude 7-(1'-bromoethyl)-2-(2-methyl-1,3-dioxolan-2-yl) benzofuran which was used immediately in the next stage. The structure of this compound was confirmed by spectral data.

Provenance & Evidence