Dicyclohexylcarbodiimide → HCID 21433935, compound

HRID 1282847Notes

Reaction equation

HRID 1282847 reaction equation
[CH3:1][C:2]1([CH3:23])[C:7]2[S:8][CH2:9][CH2:10][C:6]=2[C:5]2[C:11]([OH:22])=[CH:12][C:13]([CH:15]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH3:16])=[CH:14][C:4]=2[O:3]1.[O:24]1[CH2:29][CH2:28][N:27]([CH2:30][C:31](O)=[O:32])[CH2:26][CH2:25]1.C1(N=C=NC2CCCCC2)CCCCC1>>[CH3:23][C:2]1([CH3:1])[C:7]2[S:8][CH2:9][CH2:10][C:6]=2[C:5]2[C:11]([O:22][C:31](=[O:32])[CH2:30][N:27]3[CH2:28][CH2:29][O:24][CH2:25][CH2:26]3)=[CH:12][C:13]([CH:15]([CH2:17][CH2:18][CH2:19][CH2:20][CH3:21])[CH3:16])=[CH:14][C:4]=2[O:3]1

Participants

4

Reactant 3

HCID 10868DicyclohexylcarbodiimideHCID 4389684-Morpholineacetic acidHCID 21433925HCID 21433925, compound

Product 1

HCID 21433935HCID 21433935, compound

Procedure

By reacting 1,2-dihydro-7-(2-heptyl)-9-hydroxy-4-oxo-4H-thieno[2,3-c] [1]benzopyran with methyl magnesium bromide in a procedure similar to that described hereinabove in Example 8, there is obtained 1,2-dihydro-4,4-dimethyl-7-(2-heptyl)-9-hydroxy-4H-thieno[2,3-c] [1]benzopyran. The benzopyran is then reacted with morpholinoacetic acid and dicyclohexylcarbodiimide to yield the desired ester.

Sources & evidence

ORD record
ord-3959018b08674ec3bc28bb4d4b686878
Source dataset
uspto-grants-1976_08
Patent number
US03972880

Reaction notes

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