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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 128285Generated: October 25, 2026

Aminopyrazine → 2,7-Dimethyl-4-hydroxy-N-(pyrazinyl)-2H-[1] benzothieno-[2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxide

https://huagongshe.com/reaction/128285

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAminopyrazineHCID 78747—
Reactantmethyl 2,7-dimethyl-4-hydroxy-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxideHCID 70578267—
Product2,7-Dimethyl-4-hydroxy-N-(pyrazinyl)-2H-[1] benzothieno-[2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxideHCID 7057777639%

Reaction Steps

Prepared analogous to Example 1 from methyl 2,7-dimethyl-4-hydroxy-2H-[1] benzothieno [2,3-e]-1,2-thiazine-3-carboxylate-1,1-dioxide and amino-pyrazine with a yield of 39% of theory.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04259336
Source datasetuspto-grants-1981_03
ORD IDord-a64b9b46402a401ebbbe739bce8ff625
Source noteuspto-grants-1981_03