HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phosphorus pentachloride → 6-Chloro-2-chlorocarbonyl-benzo-[b]-thiophene-3-sulfonic acid chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phosphorus pentachloride | HCID 24819 | — |
| Reactant | HCID 23714406 | HCID 23714406 | — |
| Reactant | HCID 178527001 | HCID 178527001 | — |
| Product | 6-Chloro-2-chlorocarbonyl-benzo-[b]-thiophene-3-sulfonic acid chloride | HCID 53721120 | 72% |
Reaction Steps
Prepared analogous to Example 1(b) from monosodium 2-carboxy-6-chloro-benzo-[b]-thiophene-3-sulfonate and phosphorus (V)-chloride in the presence of phosphorus oxide trichloride with a yield of 72% of theory. The product, which crystallized upon cooling, was used in the next step without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04259336 |
| Source dataset | uspto-grants-1981_03 |
| ORD ID | ord-00ec193ecd05477c8e2d642666d89739 |
| Source note | uspto-grants-1981_03 |