Ethanol → HCID 68122098, compound

HRID 1282888Notes

Reaction equation

HRID 1282888 reaction equation
[C:1]1([CH:7]([CH:12]2[CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:13]2)[CH2:8][CH2:9][CH2:10]Br)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.C[NH:22][CH2:23][CH2:24][CH3:25].[CH2:26](O)C>>[C:1]1([C:7]([NH:22][CH2:23][CH2:24][CH3:25])([CH:12]2[CH2:20][C:19]3[C:14](=[CH:15][CH:16]=[CH:17][CH:18]=3)[CH2:13]2)[CH2:8][CH2:9][CH2:10][CH3:26])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1

Participants

4

Reactant 3

HCID 702EthanolHCID 12315N-MethylpropylamineHCID 214408322-(4-Bromo-1-phenylbutyl)-2,3-dihydro-1H-indene

Product 1

HCID 68122098HCID 68122098, compound

Conditions

Temperature
100 °C

Procedure

A solution of 1-phenyl-1-(2-indanyl)-4bromobutane in ethanol was stirred at room temperature while methylpropylamine was added. The reaction mixture was stirred several hours at about 100°C. After cooling the reaction mixture to room temperature, the solvent was removed under reduced pressure, affording 1-phenyl-1-(2-indanyl)-4-methyl-n-propylaminobutane.

Workup

  1. additionwas added
  2. temperatureAfter cooling the reaction mixture to room temperature
  3. customthe solvent was removed under reduced pressure

Sources & evidence

ORD record
ord-c2f7f20d6c794f71bdf59e382dec19e2
Source dataset
uspto-grants-1976_08
Patent number
US03972935

Reaction notes

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