Allyl glycidyl ether → 1-Allyloxy-3-n-propylamino-2-propanol

Participants

Reaction Steps

Allylglycidyl ether (94.7 g.) is added with stirring to a solution of n-propylamine (98 g., 137 ml.) in ethanol (200 ml.). The mixture is heated under reflux for 18 hours and the solvent and excess of n-propylamine are distilled off. The residual oil is distilled and the fraction b.p. 79°-85°C. at 1 m.m. is collected to give 1-allyloxy-3-n-propylamino-2-propanol.

Provenance & Evidence