HCID 23468808, compound → HCID 53636383, compound

HRID 128303Notes

Reaction equation

HRID 128303 reaction equation
[CH:1]1[C:9]2[C:8]3[CH2:10][CH2:11][CH2:12][CH2:13][C:7]=3[O:6][C:5]=2[CH:4]=[CH:3][C:2]=1[CH:14]([CH2:19][C:20]([OH:22])=[O:21])[CH2:15][C:16](O)=[O:17]>C(OC(=O)C)(=O)C>[CH:1]1[C:9]2[C:8]3[CH2:10][CH2:11][CH2:12][CH2:13][C:7]=3[O:6][C:5]=2[CH:4]=[CH:3][C:2]=1[CH:14]1[CH2:15][C:16](=[O:17])[O:21][C:20](=[O:22])[CH2:19]1

Participants

3

Reactant 1

HCID 23468808HCID 23468808, compound

Product 1

HCID 53636383HCID 53636383, compound

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent

Procedure

30.2 g (0.1 mol) of 3-(6,7,8,9-tetrahydro-2-dibenzofuranyl)-glutaric acid are refluxed with 100 ml of acetic anhydride for 11/2 hours. On leaving the cooled dark solution to stand, a crystalline precipitate forms and is filtered off after 48 hours and washed with cold toluene. The 3-(6,7,8,9-tetrahydro-2-dibenzofuranyl)-glutaric anhydride thus obtained melts at 164°-166°. After concentrating the filtrate under a waterpump vacuum, an addititonal amount of 3-(6,7,8,9-tetrahydro-2-dibenzofuranyl)-glutaric anhydride is obtained as yellowish crystals with the same melting point.

Workup

  1. customOn leaving the cooled dark solution
  2. filtrationa crystalline precipitate forms and is filtered off after 48 hours
  3. washwashed with cold toluene
  4. concentrationAfter concentrating the filtrate under a waterpump vacuum

Sources & evidence

ORD record
ord-64a9a16f2245484893eb46189f3c4605
Source dataset
uspto-grants-1981_03
Patent number
US04259338

Reaction notes

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