Pyridine → 3-Ethanesulphonyl-imidazolidin-2-on-1-carbonyl chloride

HRID 1283053Notes

Reaction equation

HRID 1283053 reaction equation
[CH2:1]([S:3]([N:6]1[CH2:10][CH2:9][NH:8][C:7]1=[O:11])(=[O:5])=[O:4])[CH3:2].[C:12](Cl)([Cl:14])=[O:13].N1C=CC=CC=1>ClCCl>[CH2:1]([S:3]([N:6]1[CH2:10][CH2:9][N:8]([C:12]([Cl:14])=[O:13])[C:7]1=[O:11])(=[O:5])=[O:4])[CH3:2]

Participants

5

Reactant 3

HCID 1049PyridineHCID 6371PhosgeneHCID 112867961-Ethylsulphonyl-imidazolidin-2-one

Product 1

HCID 117366063-Ethanesulphonyl-imidazolidin-2-on-1-carbonyl chloride

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

The N-ethanesulphonyl-imidazolidin-2-one was then suspended in dichloromethane, a large excess of phosgene was introduced at 0°C, a little pyridine was added and the mixture was left to stand overnight. The excess phosgene was then largely removed by passing in dry air and the product (3-ethanesulphonyl-imidazolidin-2-on-1-carbonyl chloride) was suspended in dichloromethane and filtered off.

Workup

  1. waitthe mixture was left
  2. customThe excess phosgene was then largely removed
  3. filtrationfiltered off

Sources & evidence

ORD record
ord-7a0647054ada431bbb7582cbacf44172
Source dataset
uspto-grants-1976_08
Patent number
US03974142

Reaction notes

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