Mesitylene → HCID 68146965, compound

HRID 1283114Notes

Reaction equation

HRID 1283114 reaction equation
C(Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[N:4][CH:3]=1.Cl.[C:11]1([CH3:19])[CH:16]=[C:15]([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1>>[N:4]1[CH:5]=[CH:6][CH:7]=[CH:2][CH:3]=1.[C:11]1([CH3:19])[CH2:16][C:15]([OH:8])([CH3:17])[CH:14]=[C:13]([CH3:18])[CH:12]=1

Participants

3

Reactant 2

HCID 7947MesityleneHCID 884383-Pyridinecarbonyl chloride, hydrochloride (1:1)

Product 1

HCID 68146965HCID 68146965, compoundYield 63%

Procedure

First, by effecting Friedel Krafts reaction between hydrochloride nicotinic acid chloride and mesitylene in accordance with Reynold C. Fuson and John J. Miller's method [cf. J.Am.Chem. Soc. 79.3477 (1957)], 3-mesitol pyridine (yield: 63%, b.p.:157.5°-158°C/4mmHg) is obtained.

Sources & evidence

ORD record
ord-47a736ad435d4828a9a42c8e92c1fe66
Source dataset
uspto-grants-1976_08
Patent number
US03974167

Reaction notes

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