Sodium Hydroxide → HCID 20499038, compound

HRID 128320Notes

Reaction equation

HRID 128320 reaction equation
[CH:1]1([CH:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12](CC(O)=O)=[CH:11][CH:10]=2)[CH3:7])[CH2:5][CH2:4][CH2:3][CH2:2]1.[OH-:19].[Na+].O.[CH2:22]([OH:24])[CH3:23]>>[C:22]([O:19][C:12]1[CH:11]=[CH:10][C:9]([NH:8][CH:6]([CH:1]2[CH2:2][CH2:3][CH2:4][CH2:5]2)[CH3:7])=[CH:14][CH:13]=1)(=[O:24])[CH3:23]

Participants

4

Reactant 3

HCID 14798Sodium HydroxideHCID 19096565Water ethanolHCID 20498903HCID 20498903, compound

Product 1

HCID 20499038HCID 20499038, compound

Procedure

A mixture of 3.62 g. of 4-(1-cyclopentylethylamino)-phenylacetic acid and 25 ml. of ethanol water (9:1) containing 0.400 g. of sodium hydroxide is stirred for 4 hours. The mixture is filtered and the residue washed with 10 ml. of ethanol-water (9:1) and dried in vacuo for 24 hours to yield 4-(1-cyclopentylethylamino)phenyl acetate as a white solid.

Workup

  1. additionA mixture of 3.62 g
  2. filtrationThe mixture is filtered
  3. washthe residue washed with 10 ml
  4. dry with materialof ethanol-water (9:1) and dried in vacuo for 24 hours

Sources & evidence

ORD record
ord-b33b2156f0a54ede8ab6be392e8eb6ce
Source dataset
uspto-grants-1981_03
Patent number
US04259352

Reaction notes

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