反应详情

To a solution of 21 g of 5-chloro-1,3-diphenyl-pyrazole-4-carboxaldehyde in 80 ml of dioxan there is added dropwise at 23° to 27° a solution of 1.11 g of sodium borohydride in 35 ml of water. The resulting suspension is stirred for a further 30 minutes and on the addition of 200 ml of water 5-chloro-4-hydroxymethyl-1,3-diphenyl-pyrazole is precipitated with a 99% yield; F 140.5°-141.5° (from toluene).

1. customis precipitated with a 99% yield
2. customF 140.5°-141.5° (from toluene)