Ethanol → HCID 86733819, compound

Participants

Reaction Steps

10 g of 5-chloro-3-p-chlorophenyl-1-phenyl-pyrazole-4-acetonitrile, 100 ml of ethanol, 1.5 ml of water and 15 ml of concentrated sulfuric acid are heated for 16 hours at boiling point. The liquid is poured on to ice, made alkaline with sodium bicarbonate solution extracted with ether and reduced in bulk. After recrystallisation from ethanol and water ethyl 5-chloro-3-p-chlorophenyl-1-phenyl-pyrazole-4-acetate is obtained with a 69% yield; F 51.5°-52.5° (from ether/petroleum ether).

Provenance & Evidence