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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1283271Generated: October 25, 2026

1-Chloro-4-iodobenzene → 1-(4'-chlorophenyl)-5-methyl-2-(1H)-pyridone

https://huagongshe.com/reaction/1283271

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Chloro-4-iodobenzeneHCID 12510—
Reactant2-Hydroxy-5-methylpyridineHCID 70482—
Product1-(4'-chlorophenyl)-5-methyl-2-(1H)-pyridoneHCID 985927875%

Reaction Steps

The reaction of 5-methyl-2-(1H)-pyridone and 1-chloro-4-iodobenzene (Aldrich Chemical Company) in the procedure of Example 1 yields 1-(4'-chlorophenyl)-5-methyl-2-(1H)-pyridone as a white crystalline solid in 75% yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03974281
Source datasetuspto-grants-1976_08
ORD IDord-89109b7f35934750af46771a14d8913f
Source noteuspto-grants-1976_08