Iodobenzene → HCID 9882638, compound

HRID 1283276Notes

Reaction equation

HRID 1283276 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9](=[O:15])[NH:10][CH:11]=[C:12]([CH3:14])[CH:13]=2)=[CH:4][CH:3]=1.I[C:17]1[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[C:9](=[O:15])[N:10]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH:11]=[C:12]([CH3:14])[CH:13]=2)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 11575IodobenzeneHCID 21406708HCID 21406708, compound

Product 1

HCID 9882638HCID 9882638, compoundYield 82%

Procedure

3-(4'Chlorophenyl)-5-methyl-1-phenyl-2-(1H)-pyridone is prepared in 82% yield by the reaction of 3-(p-chlorophenyl) -5-methyl-2-(1H)-pyridone (B. E. Witzel et al. Brit. Pat. No. 1,238,959) with iodobenzene as described in Example 1.

Sources & evidence

ORD record
ord-693e311779c24d39a4d6c2e671946f5e
Source dataset
uspto-grants-1976_08
Patent number
US03974281

Reaction notes

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