HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzaldehyde → HCID 68120239, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzaldehyde | HCID 240 | — |
| Reactant | 2-Butenoic acid, 3-amino-, ethyl ester, (2Z)- | HCID 643756 | — |
| Reactant | Ethyl 4-ethoxy-3-oxobutyrate | HCID 3016245 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 68120239 | HCID 68120239 | 65% |
Reaction Steps
After heating a solution of 10.6 g of benzaldehyde, 17.4 g of γ-ethoxyacetoacetic acid ethyl ester and 13 g of β-aminocrotonic acid ethyl ester in 80 ml of ethanol for several hours, 2-ethoxymethyl-6-methyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester is obtained, in a yield of 65% of theory, in the form of yellow crystals of melting point 112°C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03974278 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-c3ab0fd07fa3495c9801204b1402972e |
| Source note | uspto-grants-1976_08 |