Nitric Acid → HCID 86733824, compound

Participants

Reaction Steps

Fuming nitric acid (10 ml) was added to a stirred solution of 4-hydroxy-5-methoxycoumarin (m.p. 154.5°-156°; 1.63g) in chloroform (100 ml) at room temperature over 1 hour. After a further hour, the solvent was removed in vacuo and 6N hydrochloric acid (35 ml) added to the residue. Filtration gave the product, m.p. 175°-177.5°(d), (C10H7NO6 requires C, 50.64; H, 2.97; N, 5.91. Found: C, 50.54; H, 2.97; N, 5.63).

Provenance & Evidence