1,1-Diethoxycyclohexane → HCID 131710139, compound

Participants

Reaction Conditions

Reaction Steps

1.5 g. helveticoside are dissolved in 20 ml. cyclohexanone diethylketal and mixed with 1.5 g. of a cation exchanger in the H+ form (e.g. the ion exchanger known by the trade name of Lewatit S 100). The mixture is heated to 55°C while stirring, and the course of the reaction is followed by thin-layer chromatography. After about 4 hours of reaction no more helveticoside can be detected. The ion exchanger is filtered off and the solvent distilled off from the filtrate in a rotating evaporator under vacuum from a water pump. The residue is triturated with petroleum ether. Yield: 850 mg. cyclohexanone-helveticoside.

Provenance & Evidence