HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Bromonicotinic acid → 8-[alpha-(5-Bromonicotinoyloxy)-ethyl]-caffeine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Bromonicotinic acid | HCID 88707 | — |
| Reactant | Sodium | HCID 5360545 | — |
| Reactant | 8-alpha-Chloroethylcaffeine | HCID 68138365 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 8-[alpha-(5-Bromonicotinoyloxy)-ethyl]-caffeine | HCID 21518017 | — |
Reaction Steps
2.87 g of 8-α-chloroethylcaffeine are dissolved in 30 ml of anhydrous dimethylformamide, and then 2.7 g of the sodium salt of dry 5-bromonicotinic acid are added.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03975389 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-0bca3d691b6a46bd80ef682ccbbd7977 |
| Source note | uspto-grants-1976_08 |