Sodium Hydroxide → 1-Aminoanthraquinone

Participants

Reaction Steps

The same amounts of 5-nitrotetrahydroanthraquinone, aqueous sodium hydroxide solution and palladium on carbon catalyst as in Example 1 were placed in a cylindrical glass reactor having an inner volume of 500 ml and equipped with a thermometer, an agitator, a hydrogen inlet and a reflux condenser, into which was fed hydrogen at a flow rate of 1 1/min for hydrogenation while agitating the reaction mixture at room temperature for 6 hours. Thereafter, air for oxidation was fed into the reaction system at a flow rate of 1 1/min for 30 minutes. The resultant reaction product containing therein the catalyst was separated by filtration, followed by dissolution thereof in methyl cellosolve (i.e., β-hydroxyethyl methyl ether) for separating therefrom the catalyst. The resultant filtrate was condensed to obtain 2.1 grams of 1-aminoanthraquinone (at a yield of 93.1%). The purity of the 1-aminoanthraquinone was 98%.

Provenance & Evidence