Toluene → 3-Butylglycidonitrile

HRID 1283495Notes

Reaction equation

[CH:1](=[O:6])[CH2:2][CH2:3][CH2:4][CH3:5].ClC[C:9]#[N:10].[C:11]1(C)C=CC=CC=1>>[CH3:5][CH2:4][CH:3]([C:2]1([O:6][CH2:1]1)[C:9]#[N:10])[CH3:11]

Participants

Reactant 3

HCID 1140Toluene2×

HCID 7856Chloroacetonitrile

HCID 8063Pentanal

Product 1

HCID 867338343-Butylglycidonitrile

Procedure

A solution of 17.2 g. of valeraldehyde and 16.5 g. of chloroacetonitrile in 20 ml. of toluene is treated with sodium t-amylate and worked up in the manner described in Example 3, above, to give a toluene solution of 3-butylglycidonitrile (I).

Sources & evidence

ORD record: ord-1f8c048025154232b2fa7edfaa2ffa42
Source dataset: uspto-grants-1976_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03975431

Reaction notes

Loading…