Dimethylamine → HCID 21518343, compound

HRID 1283504Notes

Reaction equation

[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][C:11]([CH:13]([CH3:17])[C:14](Cl)=[O:15])=[CH:12][C:7]=2[CH2:6][CH2:5][C:4]2[CH:18]=[CH:19][CH:20]=[CH:21][C:3]1=2.[CH3:22][NH:23][CH3:24]>>[O:1]=[C:2]1[C:8]2[CH:9]=[CH:10][C:11]([CH:13]([CH3:17])[C:14]([N:23]([CH3:24])[CH3:22])=[O:15])=[CH:12][C:7]=2[CH2:6][CH2:5][C:4]2[CH:18]=[CH:19][CH:20]=[CH:21][C:3]1=2

Participants

Reactant 2

HCID 674Dimethylamine

HCID 21518331HCID 21518331, compound

Product 1

HCID 21518343HCID 21518343, compoundYield 97.2%

Procedure

Following the procedure of Example 6 but starting with 2-(5-oxo-10,11-dihydrodibenzo[a,d]cyclohepten-2-yl)propionyl chloride (10 g.) and dimethylamine (4.5 g.), 2-(5-oxo-10,11-dihydrodibenzo[a,d]cyclohepten-2-yl)-N,N-dimethylpropionamide (10 g.) is obtained in the form of an oil.

Sources & evidence

ORD record: ord-de1e0984dd354ebf851e9b1791b6d9fa
Source dataset: uspto-grants-1976_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03975437

Reaction notes

Loading…