Hydrochloric Acid → HCID 21409930, compound

Participants

Reaction Steps

To a solution of 1-[1-(Ethylaminomethyl)cyclohexyl]-4-methyl piperazine (1.5 g.,) in ether (20 ml) was added excess of ethereal HCl. The suspension was evaporated to dryness and the residual oil was re-evaporated with ethanol/ether (x2). The residue was dissolved in a minimum amount of hot ethanol, the solution was cooled and excess isopropanol was added. The solid which separated was filtered and crystallised from ethanol/isopropanol to give 1-[1-(Ethylaminomethyl)cyclohexyl]-4-methyl piperazine, dihydrochloride (0.15 g.) m.p. 231°-234°.

Provenance & Evidence