Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Peroxide → 1-(1-Oxido--thiomorpholino)-3-piperazino-5-methoxy-isoquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Peroxide | HCID 784 | — |
| 반응물 | Isopropanol | HCID 3776 | — |
| 반응물 | Hydrochloride trihydrate | HCID 21864422 | — |
| 반응물 | 1-Thiomorpholino-3-piperazino-5-methoxy-isoquinoline hemisulfate | HCID 131710434 | — |
| 용매 | Sulfuric Acid | HCID 1118 | — |
| 생성물 | 1-(1-Oxido--thiomorpholino)-3-piperazino-5-methoxy-isoquinoline | HCID 53992626 | 36% |
반응 단계
1-(1-Oxido--thiomorpholino)-3-piperazino-5-methoxy-isoquinoline was prepared analogous to Example 12 from 1-thiomorpholino-3-piperazino-5-methoxy-isoquinoline hemisulfate by oxidation with hydrogen peroxide in dilute sulfuric acid. M.p. of its hydrochloride trihydrate: 151°-153°C (decomposition; from isopropanol). Yield: 36% of theory.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US03975524 |
| 출처 데이터셋 | uspto-grants-1976_08 |
| ORD ID | ord-1e360947cc9340268df4aad6bd50d38b |
| 출처 메모 | uspto-grants-1976_08 |