HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → 2-n-Butyl-3-(3'-bromo-4'-hydroxybenzoyl)-benzofuran
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | N-bromobutanimide | HCID 67184 | — |
| Reactant | (2-Butylbenzofuran-3-yl) (4-hydroxyphenyl) ketone | HCID 96670 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-n-Butyl-3-(3'-bromo-4'-hydroxybenzoyl)-benzofuran | HCID 21518638 | — |
Reaction Steps
A mixture of 10.0 g. (0.034 mol.) of 2-n-butyl-3-(4'-hydroxybenzoyl)benzofuran and 6.1 g. (0.034 mol.) of N-bromosuccinimide in 150 ml. of damp dimethylformamide was refluxed for 12 hours. The reaction mixture was poured into water and extracted with chloroform. The extracts were washed repeatedly with water, then dried (Na2SO4) and concentrated to give 2-n-butyl-3-(3'-bromo-4'-hydroxybenzoyl)-benzofuran.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US03975537 |
| Source dataset | uspto-grants-1976_08 |
| ORD ID | ord-f514e21602dc49bba1158051335f98e8 |
| Source note | uspto-grants-1976_08 |