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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1283654Generated: November 3, 2026

p-Anisoyl chloride → 2-(4-Chlorophenyl)-3-(4-hydroxybenzoyl)benzofuran

https://huagongshe.com/reaction/1283654

Reaction equation

Participants

RoleNameHCIDCharge
Reactantp-Anisoyl chlorideHCID 7477—
Reactant2-(4-Chlorophenyl)-1-benzofuranHCID 4368312—
ReactantPyridinium chlorideHCID 10176127—
Reactant2-(4-Chlorophenyl)-3-(4-methoxybenzoyl)benzofuranHCID 21435260—
Product2-(4-Chlorophenyl)-3-(4-hydroxybenzoyl)benzofuranHCID 21435269—

Reaction Steps

When 2-(4'-chlorophenyl)benzofuran was acylated with anisoyl chloride was described in the procedure of Example 10 and the resulting 2-(4'-chlorophenyl)-3-(4'-methoxybenzoyl)benzofuran was demethylated with pyridine hydrochloride as previously described, 2-(4'-chlorophenyl)-3-(4'-hydroxybenzoyl)benzofuran was obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03975537
Source datasetuspto-grants-1976_08
ORD IDord-bb0180e88aad4302bb8aea0542a7b9d2
Source noteuspto-grants-1976_08