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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1283658Generated: November 4, 2026

Isopropylamine → 5-Methylbenzofuran

https://huagongshe.com/reaction/1283658

Reaction equation

Participants

RoleNameHCIDCharge
ReactantIsopropylamineHCID 6363—
ReactantHydrazineHCID 9321—
Reactant5-Chloro-1-benzofuranHCID 90013—
Reactant5-EthylbenzofuranHCID 19105096—
Product5-MethylbenzofuranHCID 33103—

Reaction Steps

5-ethylbenzofuran in the procedure of Example 29 for 5-chlorobenzofuran followed by the synthetic steps of hydrazine reduction, acylation, demethylation, epoxide formation and opening of the epoxide with isopropylamine as described therein gives, ultimately, the following substituted benzofurans:

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03975537
Source datasetuspto-grants-1976_08
ORD IDord-33ca59347ad94a29a791f4f9bbce4c7d
Source noteuspto-grants-1976_08