p-Anisoyl chloride → Pyridinium chloride

HRID 1283664Notes

Reaction equation

HRID 1283664 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([C:10]2[O:11][C:12]3[CH:18]=[CH:17][CH:16]=[CH:15][C:13]=3[CH:14]=2)[CH:7]=[CH:8][CH:9]=1)([O-:3])=[O:2].[C:19]([Cl:29])(=[O:28])[C:20]1[CH:25]=[CH:24][C:23]([O:26]C)=[CH:22][CH:21]=1>>[ClH:29].[N:1]1[CH:4]=[CH:9][CH:8]=[CH:7][CH:6]=1.[OH:26][C:23]1[CH:24]=[CH:25][C:20]([C:19]([C:14]2[C:13]3[CH:15]=[CH:16][CH:17]=[CH:18][C:12]=3[O:11][C:10]=2[C:6]2[CH:7]=[CH:8][CH:9]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=2)=[O:28])=[CH:21][CH:22]=1

Participants

4

Reactant 2

HCID 7477p-Anisoyl chlorideHCID 12391456HCID 12391456, compound

Product 2

HCID 10176127Pyridinium chlorideHCID 21518614HCID 21518614, compound

Procedure

Acylation of 2-m-nitrophenylbenzofuran with anisoyl chloride is accomplished as described in the procedure of Example 10. Demethylation with pyridine hydrochloride as previously described gives 3-(4'-hydroxybenzoyl)- 2-(3'-nitrophenyl)benzofuran.

Sources & evidence

ORD record
ord-70e9e367bebd45cab19405ffb77d1d1b
Source dataset
uspto-grants-1976_08
Patent number
US03975537

Reaction notes

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