反应详情

To a solution of 0.288 g. of 2-(5-oxo-5H-dibenzo[a,d]cyclohepten-2 -yl)propanal in 3 ml. of methanol is added a solution of 0.111 g. of semicarbazide hydrochloride in 0.5 ml. of water, followed by 1 drop of pyridine. The mixture is refluxed briefly and then poured into water. The product is extracted with ethyl acetate and the extract washed, dried and evaporated to afford, upon crystallization from ethyl acetate/hexane, 2-(5-oxo-5H-dibenzo[a,d]-cyclohepten-2-yl)propanal semicarbazone.

1. temperatureThe mixture is refluxed briefly
2. extractionThe product is extracted with ethyl acetate
3. washthe extract washed
4. customdried
5. customevaporated